Background. Retinitis pigmentosa (RP) comprises a group of inherited disorders in which patients typically lose night vision in\nadolescence and then lose peripheral vision in young adulthood before eventually losing central vision later in life. A\nretrospective case-control study was performed to evaluate differences in ocular biometric parameters in primary angle-closure\nglaucoma (PACG) patients with and without concomitant RP to determine whether a relationship exists between PACG and\nRP. Methods. We used ultrasound biomicroscopy (UBM) to measure anterior chamber depth (ACD). A-scan biometry was\ncarried out to measure lens thickness (LT) and axial length (AL). Propensity score matching and mixed linear regression model\nanalysis were conducted. 23 patients with chronic primary angle-closure glaucoma (CPACG) associated with RP, 21 patients\nwith acute primary angle-closure glaucoma (APACG) associated with RP, 270 patients with CPACG, and 269 patients with\nAPACG were recruited for this study. Results. There were no significant differences on ACDs, ALs, and relative lens position\n(RLP) (P > 0 05) between patients with PACG associated with RP and patients with PACG; however, patients with APACG\nassociated with RP had a significantly greater LT than patients with APACG (P < 0 05). Conclusion. Patients with PACG\nassociated with RP had the same biometric parameter characteristic as the patients with CPACG and APACG. This may suggest\nthat RP is a coincidental relationship with angle-closure glaucoma.
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